Two Monthly MHeNs Translational Neuroscience Lecture

Second lecture:
Dr. Yasir Syed, School of Biosciences Cardiff University
Title: “Neurodevelopmental mechanism in the 1q21.1deletion Syndrome”

Monday May 14th, 2018 at 11 AM
Location: Jo Ritzenzaal (room S0.007), Oxfordlaan 55, Maastricht
Lunch: Bandidos

Neurodevelopmental mechanism in the 1q21.1deletion Syndrome
Chromosomal deletions at 1q21.1 represent one of the highest known genetic risk factor for the development of psychiatric disorders. Individuals with 1q21.1 deletion can present with many clinical complications including microcephaly, learning disorders and cardiac anomalies. The mechanisms underlying the symptoms in 1q21.1 remain unclear. The talk will highlight the recent findings on cellular and immunological mechanisms underlying the neuropsychiatric phenotype in patients with 1q21.1 deletions.

Short Bio
Dr. Yasir Syed is group leader at Neuroscience and Mental Health Research Institute, Cardiff University.  His lab works on disease progression modelling in neurodegenerative and neuropsychiatric diseases using patient derived stem cells.   Com-plementary interest focuses on mechanisms of CNS regeneration with a particular focus on remyelination, an adult stem cell-mediated process in which new myelin sheaths are restored to demyelinated axons. Dr. Syed did his PhD from MaxPlanck Institute of Experimental Medicine, Germany and postdoctoral research at Welcome Trust-MRC Cambridge Stem Cell Institu-te before joining Cardiff University. He has number of publications and patent to his credit, where he has identified extrinsic (environmental) and intrinsic (transcriptional) factors that regulate the glial differentiation during development and disease.

Participation is free, but please note that registration is obligatory. Due to limited places (70) early registration is recommended.


Register here.